Which of the following medications is known for causing constipation?

Opioids are well-known for their side effects, particularly in causing constipation. This effect occurs because opioids bind to specific receptors in the gastrointestinal tract, leading to decreased motility and slower transit of stool through the intestines. As a result, the stool becomes harder and more difficult to pass, which can lead to conditions such as bowel obstruction or fecal impaction if not managed properly.

Healthcare providers often take this into consideration when prescribing opioids, particularly to patients who may already be at risk for constipation. They may recommend the concurrent use of laxatives or stool softeners to mitigate this side effect. Understanding this relationship is crucial for individuals working in pharmacy and healthcare, as managing medication-related side effects is an important aspect of patient care.